ariadne.ai

SPATIAL

Cloud-based spatial omics here in your web browser No coding, no specialized hardware. Top-tier accuracy in registration and segmentation. Supports proteomics, transcriptomics, metabolomics and more.
Tailored by ariadne.ai to your needs.

Precise segmentation

Precise cell segmentation, even for neurons and glia. Detailed morphometric analyses.

Best-in-class registration

Robust elastic registration. Unlimited scalability. Co-register between any correlated modalities.

3D support

Full 3d support. View you tissue in unprecedented detail.

Investigate tissue microstructure

Define cell types automatically or manually. Discover tissue microstructure.

Highly scalable

Unlimited scalability in both 2 and 3 dimensions. From megabytes to terabytes.

Limitless customization

Limitless customization. You dream it up, we’ll make it happen.

Contact us
for a free trial

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a simple workflow

SPATIAL is effortlessly accessible through any web browser.

1. Create your account

Create your account online. Start with a free trial!

2. Upload

Upload your multiplex data in any format of your choice. Directly from your web browser.

3. Visualize

Explore your data. No matter how large your dataset, SPATIAL has you covered.

4. Analysis

Pixel-perfect registration and segmentation. Dive into tissue microstructure.

5. Tailored Customization and Support

SPATIAL is your virtual data science team. You need an analysis that isn’t supported yet? We’ll make it work for you.

6. Share

Download all data at any time, share web links to your data with colleagues or in publications.

Book your demo now

Discover our pricing model by scheduling a demo call! Exclusive academic and facility rates available.

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Testimonials

Happy clients share their thoughts about us.
See what they say!

"Super responsive"

The ariadne.ai team was always there to handle our custom requests quickly and with great scientific rigor. Their neuron and glia segmentation is fantastic.


Bahareh Ajami

Assistant Professor, Oregon Health and Science

"Scientifically excellent"

They supported our lab’s immuno-oncology work from start to finish. We had some challenging data for them, and they tuned their registration and segmentation to handle it perfectly.


Ferdinando Pucci

Assistant Professor, Oregon Health and Science

"Great segmentation"

Their neuron and glia segmentation is the best I’ve seen yet.


Dr. Oliver Braubach

Director of R&D, Canopy Biosciences

"Scientifically excellent"

They supported our lab’s immuno-oncology work from start to finish. We had some challenging data for them, and they tuned their registration and segmentation to handle it perfectly.


Ferdinando Pucci

Assistant Professor, Oregon Health and Science

FAQ

Frequently Asked Questions

We support all existing multiplex image file types. All common ones are automatically recognized and converted. For less common file types, we will implement additional support as needed.

SPATIAL is designed for analyzing multiplexed 2D and 3D data, supporting any spatial omics modality, device, or protocol. Our platform has been used with data from all major commercial proteomics and transcriptomics devices, as well as numerous custom protocols. Contact us to learn more about our capabilities.

SPATIAL works on any modern browser, leveraging cloud computing for processing. This means you can use our platform even on low-powered devices like tablets.

The basic workflow includes the following steps: image registration, cell segmentation, marker mapping, calculation of cell-level morphometrics, cell type gating, and spatial analysis. We offer customization to meet any specific analysis needs. All data is available for download at any stage.

It's fully elastic, and scalable to arbitrary size. Some data can't be analyzed without this, but we've found that even nominally well-aligned data can profit from running our registration pipeline. Pixel-perfect precision is essential to get minimal cross-talk!

We segment cells using image channels that outline cellular morphology, optionally combined with a nucleus channel. The method works on any image channel on which cell outlines can be made out. For example, antibody-derived stains of CD45 can be used, but H&E or Hematoxylin staining works as well. Multiple markers can be combined for comprehensive cell delineation.

There is no set limit on dataset size. Data quotas vary by subscription level. Contact us for details.

Subscription fees are invoiced to institutions, payable via bank transfer.

Results are accessible through the SPATIAL browser interface and downloadable in standard formats like TIFF or CSV.

We take data security very seriously. All data provided by our customers is kept strictly confidential and maintained on secure infrastructure.

Our services are utilized by academic and industry labs worldwide, supported by a team with over 10 years of experience in biomedical image analysis. Our contributions include numerous publications in top-tier journals. Please head to our case studies section for a sample!

For more information, schedule a personalized remote demo right here on this website! We're also happy to arrange an on-site visit if we're in your area.
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